Across TCGA cell cohorts, MYO1C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,734 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MYO1C-associated GO terms across cancer lineages are Anterograde neuronal dense core vesicle transport, Mitotic centrosome separation, and Negative regulation of cell killing. Each is linked with MYO1C in more than 15 cancer types. Because this analysis shows association rather than direction, both MYO1C-to-partner and partner-to-MYO1C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1C→partner) and Y-score (partner→MYO1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Anterograde neuronal dense core vesicle transport →	+0.239	+1.481	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Mitotic centrosome separation →	+0.143	+1.165	.001	.002	3	15
URINARY_TRACT	Negative regulation of cell killing →	+0.283	+1.647	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.073	+1.358	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.196	+1.413	.002	.001	3	15
KIDNEY	Cytosolic transport →	+0.076	+0.824	.003	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,734 associations by consensus.

Exploration

MYO1C survival (RNA) · tumor vs normal (RNA) · all MYO1C data types