MYO19

Across TCGA patient cohorts, MYO19 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO19-associated genes across cancer lineages are eEF2, GAPDH, and ATM. Each is linked with MYO19 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO19-to-partner and partner-to-MYO19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by MYO19-low versus MYO19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO19→partner) and Y-score (partner→MYO19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.252	+1.201	.023	.028	3	3
STAD	GAPDH →	+0.528	+3.000	.001	.033	3	2
UCEC	ATM →	-0.551	-1.893	<.001	<.001	3	2
COAD	Claudin-7 →	+0.709	+3.178	.030	.010	3	2
UCEC	JNK_pT183_Y185 →	-0.167	-1.925	.001	.004	3	2
UCEC	MEK1 →	+0.438	+3.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

eEF2 by MYO19 expression — UCEC

Explore this box plot interactively →