MYO19

Across TCGA cell cohorts, MYO19 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,736 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MYO19-associated GO terms across cancer lineages are DNA replication proofreading, DNA replication checkpoint signaling, and DNA strand elongation involved in DNA replication. Each is linked with MYO19 in more than 16 cancer types. Because this analysis shows association rather than direction, both MYO19-to-partner and partner-to-MYO19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication proofreading grouped by MYO19-low versus MYO19-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO19→partner) and Y-score (partner→MYO19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DNA replication proofreading →	+0.183	+0.975	<.001	<.001	3	17
BONE	DNA replication checkpoint signaling →	+0.206	+1.392	.005	.001	3	17
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.249	+1.206	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.092	+1.149	<.001	<.001	3	17
BONE	DNA recombination →	+0.088	+1.277	.001	<.001	3	17
PANCREAS	Cell cycle DNA replication →	+0.136	+1.121	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,736 associations by consensus.

DNA replication proofreading by MYO19 expression — SKIN

Explore this box plot interactively →