MYO18B

Across TCGA cell cohorts, MYO18B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,617 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MYO18B-associated GO terms across cancer lineages are Regulation of skeletal muscle contraction, Internal peptidyl-lysine acetylation, and Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Each is linked with MYO18B in more than 4 cancer types. Because this analysis shows association rather than direction, both MYO18B-to-partner and partner-to-MYO18B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of skeletal muscle contraction grouped by MYO18B-low versus MYO18B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO18B→partner) and Y-score (partner→MYO18B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of skeletal muscle contraction →	-0.119	-0.084	<.001	.007	3	5
SOFT_TISSUE	Internal peptidyl-lysine acetylation →	+0.086	+2.038	<.001	<.001	3	4
LUNG_SCLC	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	+0.059	+0.418	<.001	<.001	3	4
SOFT_TISSUE	Muscle system process →	-0.063	-2.241	<.001	<.001	3	4
SOFT_TISSUE	Basement membrane disassembly →	+0.783	+1.978	<.001	<.001	3	4
BONE	Transsulfuration →	+0.186	+1.403	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,617 associations by consensus.

Regulation of skeletal muscle contraction by MYO18B expression — URINARY_TRACT

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