MYO18B

Across TCGA cell cohorts, MYO18B mutation is significantly associated with the RNA expression of many other genes, with 1,370 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYO18B-associated genes across cancer lineages are CTDSP2, SHF, and ADO. Each is linked with MYO18B in more than 3 cancer types. Because this analysis shows association rather than direction, both MYO18B-to-partner and partner-to-MYO18B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTDSP2 grouped by MYO18B-low versus MYO18B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO18B→partner) and Y-score (partner→MYO18B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CTDSP2 →	-0.635	-3.169	.003	.008	3	4
LUNG_NSCLC_LUAD	SHF →	-0.825	-2.807	<.001	<.001	3	3
LUNG_NSCLC_LUAD	ADO →	-0.349	-3.459	.002	.001	3	3
LARGE_INTESTINE	PIGL →	+0.644	+3.459	.002	.001	3	3
LARGE_INTESTINE	GGT7 →	-1.098	-2.278	.002	.001	3	3
LARGE_INTESTINE	TIPIN →	+0.548	+1.850	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,370 associations by consensus.

CTDSP2 by MYO18B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →