Across TCGA patient cohorts, MYO18A protein abundance is significantly associated with the RNA expression of many other genes, with 14,404 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MYO18A-associated genes across cancer lineages are ITK, CD48, and IFIT3. Each is linked with MYO18A in more than 5 cancer types. Because this analysis shows association rather than direction, both MYO18A-to-partner and partner-to-MYO18A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO18A→partner) and Y-score (partner→MYO18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ITK →	+0.853	+0.227	<.001	<.001	3	6
OV	CD48 →	+1.050	+0.252	.001	.003	3	6
HNSC	IFIT3 →	+1.102	+0.173	.002	.005	3	6
LSCC	TESPA1 →	+0.666	+0.192	<.001	<.001	3	6
OV	IRF8 →	+0.808	+0.199	<.001	.001	3	6
OV	GZMA →	+1.527	+0.287	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,404 associations by consensus.

Exploration

MYO18A survival (RNA) · tumor vs normal (RNA) · all MYO18A data types