Across TCGA patient cohorts, MYO18A mutation is significantly associated with the total protein of many other genes, with 85 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO18A-associated genes across cancer lineages are PCNA, CD31, and MEK1. Each is linked with MYO18A in more than 3 cancer types. Because this analysis shows association rather than direction, both MYO18A-to-partner and partner-to-MYO18A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO18A→partner) and Y-score (partner→MYO18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.200	+2.502	<.001	.001	3	4
LUSC	CD31 →	-0.226	-2.990	.010	.036	3	3
COAD	MEK1 →	+0.266	+2.112	<.001	.003	3	3
UCEC	eEF2 →	+0.348	+1.502	<.001	<.001	3	3
UCEC	EGFR_pY1068 →	-0.291	-2.039	<.001	<.001	3	3
COAD	N-Ras →	-0.119	-3.169	.017	.017	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

Exploration

MYO18A survival (RNA) · tumor vs normal (RNA) · all MYO18A data types