MYO16

Across TCGA patient cohorts, MYO16 protein abundance is significantly associated with the RNA expression of many other genes, with 3,525 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MYO16-associated genes across cancer lineages are CTSZ, TRADD, and MAP4K1. Each is linked with MYO16 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYO16-to-partner and partner-to-MYO16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYO16 versus CTSZ in GBM, with a Pearson correlation of -0.91.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO16→partner) and Y-score (partner→MYO16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTSZ →	-1.795	-1.164	.004	.005	3	1
GBM	TRADD →	-0.734	-1.163	.001	.005	3	1
GBM	MAP4K1 →	-0.764	-1.164	.003	.005	3	1
GBM	RSRC2 →	+0.439	+1.163	<.001	.005	3	1
GBM	TRIM38 →	-1.696	-1.163	<.001	.005	3	1
GBM	NNT →	+0.554	+1.163	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,525 associations by consensus.

MYO16 vs CTSZ — GBM

Explore this scatter interactively →