MYO16-AS1

Across TCGA pan-cancer cohorts, MYO16-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MYO16-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MYO16-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MYO16-AS1 expression acts as an unfavorable survival marker, although some lineages such as CESC and LAML show a favorable association.

KIRC, SKCM, and HNSC are the cancer types where MYO16-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.523	0.669	<.001	136	view →
SKCM	OS	Tertile	II,III,IV	0.718	0.870	<.001	81	view →
HNSC	DFS	Tertile	All	0.255	0.506	<.001	73	view →
PAAD	DFS	Median	All	0.183	0.386	<.001	58	view →
COAD	DFS	Tertile	All	0.586	0.738	<.001	55	view →
OV	DFS	Median	III,IV	0.476	0.586	.001	48	view →
CESC	DFS	Quartile	II,III,IV	0.826	0.498	.004	34	view →
UCEC	OS	Tertile	All	0.891	0.938	.003	34	view →
LAML	DFS	Median	All	0.515	0.219	.001	30	view →
BLCA	OS	Quartile	All	0.511	0.657	.005	30	view →
LUSC	OS	Quartile	II,III,IV	0.489	0.739	.009	25	view →
UCS	OS	Tertile	IV	0.766	0.268	.033	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MYO16-AS1–KIRC (OS)

Open the KIRC breakdown →