MYO15B

Across TCGA cell cohorts, MYO15B mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYO15B-associated genes across cancer lineages are HRG, ZIC3, and WFDC12. Each is linked with MYO15B in more than 1 cancer types. Because this analysis shows association rather than direction, both MYO15B-to-partner and partner-to-MYO15B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HRG grouped by MYO15B-low versus MYO15B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO15B→partner) and Y-score (partner→MYO15B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HRG →	+0.353	+3.855	<.001	.007	3	1
BLOOD_Leukemia	ZIC3 →	+0.015	+4.060	<.001	.003	3	1
BLOOD_Leukemia	WFDC12 →	+0.198	+3.874	<.001	.005	3	1
BLOOD_Leukemia	DEFB4A →	+0.096	+4.269	.001	.002	3	1
BLOOD_Leukemia	CYP4A11 →	+0.040	+3.705	<.001	.007	3	1
BLOOD_Leukemia	TMEM244 →	+0.277	+3.551	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

HRG by MYO15B expression — BLOOD_Leukemia

Explore this box plot interactively →