MYNN

Across TCGA patient cohorts, MYNN mutation is significantly associated with the RNA expression of many other genes, with 2,640 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYNN-associated genes across cancer lineages are OR6K5P, MIR4797, and PDE4DIPP3. Each is linked with MYNN in more than 1 cancer types. Because this analysis shows association rather than direction, both MYNN-to-partner and partner-to-MYNN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6K5P grouped by MYNN-low versus MYNN-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYNN→partner) and Y-score (partner→MYNN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	OR6K5P →	+0.267	+3.853	<.001	.008	3	2
READ	MIR4797 →	+0.819	+5.054	<.001	.001	3	2
BLCA	PDE4DIPP3 →	+0.173	+3.623	<.001	.004	3	2
BRCA	MIR101-2 →	+0.462	+4.198	.007	.009	3	2
BRCA	RNU6-666P →	+0.378	+4.800	<.001	.006	3	2
BRCA	HNRNPH1P2 →	+0.041	+5.270	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,640 associations by consensus.

OR6K5P by MYNN expression — STAD

Explore this box plot interactively →