MYNN

Across TCGA cell cohorts, MYNN mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYNN-associated genes across cancer lineages are TBX22, HTR1E, and TFDP3. Each is linked with MYNN in more than 1 cancer types. Because this analysis shows association rather than direction, both MYNN-to-partner and partner-to-MYNN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBX22 grouped by MYNN-low versus MYNN-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYNN→partner) and Y-score (partner→MYNN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBX22 →	+0.030	+3.632	<.001	.003	3	1
LARGE_INTESTINE	HTR1E →	+0.070	+3.345	<.001	.007	3	1
LARGE_INTESTINE	TFDP3 →	+0.031	+3.196	<.001	.007	3	1
LARGE_INTESTINE	RIPPLY2 →	+0.494	+3.196	<.001	.007	3	1
LARGE_INTESTINE	UBE2QL1 →	+0.262	+3.766	<.001	.004	3	1
LARGE_INTESTINE	TMEM233 →	+0.293	+3.196	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

TBX22 by MYNN expression — LARGE_INTESTINE

Explore this box plot interactively →