Across TCGA patient cohorts, MYMK mutation is significantly associated with the RNA expression of many other genes, with 1,370 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYMK-associated genes across cancer lineages are CICP6, RNY4P23, and TRAJ25. Each is linked with MYMK in more than 1 cancer types. Because this analysis shows association rather than direction, both MYMK-to-partner and partner-to-MYMK results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYMK→partner) and Y-score (partner→MYMK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CICP6 →	+0.021	+5.096	<.001	.008	3	2
LUAD	RNY4P23 →	+0.655	+4.690	<.001	.003	3	2
LUAD	TRAJ25 →	+0.767	+4.659	.002	.004	3	2
LUAD	RN7SKP143 →	+0.203	+5.315	<.001	.003	3	2
UCEC	FBXO7 →	+0.410	+2.523	.002	.001	3	2
UCEC	XPNPEP1 →	+0.540	+3.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,370 associations by consensus.

Exploration

MYMK survival (RNA) · tumor vs normal (RNA) · all MYMK data types