Across TCGA patient cohorts, MYMK mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYMK-associated genes across cancer lineages are 14-3-3_beta, A-Raf_pS299, and ERK2. Each is linked with MYMK in more than 1 cancer types. Because this analysis shows association rather than direction, both MYMK-to-partner and partner-to-MYMK results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYMK→partner) and Y-score (partner→MYMK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.123	-2.794	.005	.003	3	1
UCEC	A-Raf_pS299 →	-0.103	-3.169	.048	.019	3	1
UCEC	ERK2 →	+0.193	+3.321	.022	.010	3	1
UCEC	GATA6 →	-0.168	-1.992	.015	.031	3	1
UCEC	MEK1 →	+0.383	+3.169	.016	.018	3	1
UCEC	Mre11 →	-0.079	-2.115	.034	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

MYMK survival (RNA) · tumor vs normal (RNA) · all MYMK data types