Across TCGA cell cohorts, MYMK mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYMK-associated genes across cancer lineages are SNTN, RTP2, and SH3GL2. Each is linked with MYMK in more than 1 cancer types. Because this analysis shows association rather than direction, both MYMK-to-partner and partner-to-MYMK results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYMK→partner) and Y-score (partner→MYMK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SNTN →	+0.038	+4.922	<.001	.009	3	1
BLOOD_Leukemia	RTP2 →	+0.019	+5.539	<.001	.003	3	1
LARGE_INTESTINE	SH3GL2 →	+1.602	+3.474	<.001	.003	3	1
LARGE_INTESTINE	UFSP2 →	+0.728	+3.082	<.001	.007	3	1
LARGE_INTESTINE	CPLX4 →	+0.025	+2.444	<.001	.008	3	1
LARGE_INTESTINE	MTNR1A →	+0.437	+3.064	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

MYMK survival (RNA) · tumor vs normal (RNA) · all MYMK data types