MYLK4

Across TCGA cell cohorts, MYLK4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,952 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MYLK4-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with MYLK4 in more than 12 cancer types. Because this analysis shows association rather than direction, both MYLK4-to-partner and partner-to-MYLK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by MYLK4-low versus MYLK4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYLK4→partner) and Y-score (partner→MYLK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.090	-0.318	.002	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.090	-0.318	.002	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.094	-0.309	.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.108	+0.209	.002	.007	3	11
BREAST	Regulation of mRNA processing →	+0.096	+0.346	<.001	.005	3	11
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.093	+0.242	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,952 associations by consensus.

Cilium or flagellum-dependent cell motility by MYLK4 expression — UPPER_AERODIGESTIVE_TRACT

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