MYLK2

Across TCGA patient cohorts, MYLK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,503 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MYLK2-associated proteins across cancer lineages are RIF1, TPX2, and DNMT1_S714. Each is linked with MYLK2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MYLK2-to-partner and partner-to-MYLK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYLK2 versus RIF1 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYLK2→partner) and Y-score (partner→MYLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RIF1 →	+0.349	+0.245	<.001	<.001	3	5
LUAD	TPX2 →	+0.930	+0.271	<.001	<.001	3	5
LUAD	DNMT1_S714 →	+0.646	+0.193	<.001	.001	3	5
HNSC	KRT19 →	-0.864	-1.057	.008	.002	3	4
BRCA	TPX2_S738 →	+1.054	+0.353	<.001	<.001	3	4
BRCA	CHEK1 →	+0.600	+0.312	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,503 associations by consensus.

MYLK2 vs RIF1 — BRCA

Explore this scatter interactively →