MYLK2

Across TCGA patient cohorts, MYLK2 protein abundance is significantly associated with the protein abundance of many other proteins, with 12,644 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MYLK2-associated proteins across cancer lineages are THRAP3_S535, MLLT1_S315, and RNMT_T77. Each is linked with MYLK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYLK2-to-partner and partner-to-MYLK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYLK2 versus THRAP3_S535 in BRCA, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYLK2→partner) and Y-score (partner→MYLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	THRAP3_S535 →	+1.849	+1.524	<.001	.003	3	3
BRCA	MLLT1_S315 →	+1.729	+1.165	.004	.001	3	3
OV	RNMT_T77 →	+1.433	+0.946	<.001	<.001	3	2
BRCA	RPL37 →	+1.083	+1.329	<.001	<.001	3	2
BRCA	SLC4A4_S213 →	+2.266	+1.419	<.001	.007	3	2
BRCA	SLC4A4_S257 →	+2.266	+1.419	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,644 associations by consensus.

MYLK2 vs THRAP3_S535 — BRCA

Explore this scatter interactively →