MYLK

Across TCGA patient cohorts, MYLK protein abundance is significantly associated with the RNA expression of many other genes, with 18,890 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MYLK-associated genes across cancer lineages are MYL9, CNN1, and AOC3. Each is linked with MYLK in more than 9 cancer types. Because this analysis shows association rather than direction, both MYLK-to-partner and partner-to-MYLK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYLK versus MYL9 in BRCA, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYLK→partner) and Y-score (partner→MYLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYL9 →	+1.327	+0.620	<.001	<.001	3	10
UCEC	CNN1 →	+2.545	+1.055	<.001	<.001	3	10
OV	AOC3 →	+1.347	+0.641	<.001	<.001	3	10
OV	DDR2 →	+1.298	+0.494	<.001	<.001	3	10
UCEC	LMOD1 →	+1.742	+0.937	<.001	<.001	3	10
GBM	RCAN2 →	+1.460	+0.534	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,890 associations by consensus.

MYLK vs MYL9 — BRCA

Explore this scatter interactively →