MYLK

Across TCGA cell cohorts, MYLK RNA expression is significantly associated with the go_rna of many other GO terms, with 5,802 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MYLK-associated GO terms across cancer lineages are Aorta smooth muscle tissue morphogenesis, Tonic smooth muscle contraction, and Positive regulation of focal adhesion assembly. Each is linked with MYLK in more than 17 cancer types. Because this analysis shows association rather than direction, both MYLK-to-partner and partner-to-MYLK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aorta smooth muscle tissue morphogenesis grouped by MYLK-low versus MYLK-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYLK→partner) and Y-score (partner→MYLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Aorta smooth muscle tissue morphogenesis →	+1.671	+3.819	<.001	<.001	3	18
SKIN	Tonic smooth muscle contraction →	+1.638	+2.101	<.001	<.001	3	18
BONE	Positive regulation of focal adhesion assembly →	+0.180	+2.314	<.001	<.001	3	15
BONE	Blood vessel morphogenesis →	+0.094	+2.732	<.001	<.001	3	13
LIVER	Regulation of glutamate uptake involved in transmission of nerve impulse →	+0.240	+2.373	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Regulation of plasminogen activation →	+0.366	+4.381	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,802 associations by consensus.

Aorta smooth muscle tissue morphogenesis by MYLK expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →