Across TCGA pan-cancer cohorts, MYL6P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MYL6P2’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MYL6P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MYL6P2 is over-expressed in tumor, although a few such as THCA and STAD show the opposite, repressed pattern.
HNSC, COAD, and THCA are the cancer types where MYL6P2 tumor–normal differential expression is most reproducible.