Across TCGA patient cohorts, MYL6B mutation is significantly associated with the RNA expression of many other genes, with 507 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYL6B-associated genes across cancer lineages are RNA5SP204, FADS1, and CCDC15. Each is linked with MYL6B in more than 1 cancer types. Because this analysis shows association rather than direction, both MYL6B-to-partner and partner-to-MYL6B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL6B→partner) and Y-score (partner→MYL6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP204 →	+0.406	+2.303	<.001	.004	3	2
UCEC	FADS1 →	+0.836	+3.338	.001	.005	3	1
UCEC	CCDC15 →	+0.460	+2.732	.003	.003	3	1
UCEC	GUF1 →	+0.559	+2.711	<.001	.003	3	1
UCEC	ZDHHC7 →	+0.412	+3.345	.009	.005	3	1
UCEC	OTULIN →	+0.451	+3.818	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 507 associations by consensus.

Exploration

MYL6B survival (RNA) · tumor vs normal (RNA) · all MYL6B data types