MYL6

Across TCGA cell cohorts, MYL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,510 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MYL6-associated GO terms across cancer lineages are Muscle filament sliding, Actin-myosin filament sliding, and Bleb assembly. Each is linked with MYL6 in more than 13 cancer types. Because this analysis shows association rather than direction, both MYL6-to-partner and partner-to-MYL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Muscle filament sliding grouped by MYL6-low versus MYL6-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL6→partner) and Y-score (partner→MYL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Muscle filament sliding →	+0.242	+0.942	<.001	<.001	3	14
STOMACH	Actin-myosin filament sliding →	+0.234	+1.290	<.001	.002	3	14
BONE	Bleb assembly →	+0.293	+0.929	<.001	<.001	3	11
LIVER	Response to increased oxygen levels →	+0.150	+1.320	.001	<.001	3	11
SOFT_TISSUE	Negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II →	+1.092	+0.774	.002	.007	3	10
LUNG_NSCLC_LUSC	D-glucuronate catabolic process to D-xylulose 5-phosphate →	-0.278	-1.185	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,510 associations by consensus.

Muscle filament sliding by MYL6 expression — CNS

Explore this box plot interactively →