Across TCGA patient cohorts, MYL5 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,832 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MYL5-associated proteins across cancer lineages are LMNB2, CTBP1, and XPC. Each is linked with MYL5 in more than 3 cancer types. Because this analysis shows association rather than direction, both MYL5-to-partner and partner-to-MYL5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL5→partner) and Y-score (partner→MYL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LMNB2 →	+0.337	+0.272	<.001	.001	3	4
OV	CTBP1 →	+0.389	+0.741	<.001	<.001	3	4
BRCA	XPC →	+0.206	+0.573	<.001	<.001	3	3
LUAD	PPIB →	-0.383	-0.542	<.001	<.001	3	3
BRCA	PSME4 →	-0.309	-0.644	.002	.005	3	3
BRCA	PGPEP1 →	+0.414	+0.801	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,832 associations by consensus.

Exploration

MYL5 survival (RNA) · tumor vs normal (RNA) · all MYL5 data types