Across TCGA cell cohorts, MYL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,224 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MYL5-associated GO terms across cancer lineages are Regulation of macroautophagy, Cilium or flagellum-dependent cell motility, and Meiotic chromosome segregation. Each is linked with MYL5 in more than 11 cancer types. Because this analysis shows association rather than direction, both MYL5-to-partner and partner-to-MYL5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL5→partner) and Y-score (partner→MYL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of macroautophagy →	+0.102	+1.467	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.088	-0.687	<.001	.005	3	11
SOFT_TISSUE	Meiotic chromosome segregation →	-0.093	-1.140	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.088	-0.687	<.001	.005	3	11
OESOPHAGUS	Cilium movement involved in cell motility →	-0.111	-1.361	<.001	.004	3	11
OVARY	Fatty acid catabolic process →	+0.075	+1.311	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,224 associations by consensus.

Exploration

MYL5 survival (RNA) · tumor vs normal (RNA) · all MYL5 data types