MYL3

Across TCGA cell cohorts, MYL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 359 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYL3-associated GO terms across cancer lineages are Regulation of muscle filament sliding, Liver development, and Axoneme assembly. Each is linked with MYL3 in more than 5 cancer types. Because this analysis shows association rather than direction, both MYL3-to-partner and partner-to-MYL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of muscle filament sliding grouped by MYL3-low versus MYL3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL3→partner) and Y-score (partner→MYL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of muscle filament sliding →	+0.926	+0.572	<.001	.007	3	6
LARGE_INTESTINE	Liver development →	+0.048	+1.086	.001	.005	3	3
LARGE_INTESTINE	Axoneme assembly →	-0.032	-1.067	.003	.004	2	4
LARGE_INTESTINE	Motile cilium assembly →	-0.022	-0.660	.004	.007	2	4
SOFT_TISSUE	Vesicle targeting, rough ER to cis-Golgi →	+0.065	+0.466	<.001	.002	3	3
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.060	+0.687	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 359 associations by consensus.

Regulation of muscle filament sliding by MYL3 expression — LARGE_INTESTINE

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