MYL2

Across TCGA patient cohorts, MYL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,680 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MYL2-associated GO terms across cancer lineages are Positive regulation of the force of heart contraction, Lymphocyte migration, and Regulation of blood vessel endothelial cell migration. Each is linked with MYL2 in more than 14 cancer types. Because this analysis shows association rather than direction, both MYL2-to-partner and partner-to-MYL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of the force of heart contraction grouped by MYL2-low versus MYL2-high in PAAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL2→partner) and Y-score (partner→MYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	Positive regulation of the force of heart contraction →	-0.108	-0.287	<.001	<.001	3	15
SCLC	Lymphocyte migration →	+0.067	+0.077	.003	.004	3	14
STAD	Regulation of blood vessel endothelial cell migration →	+0.042	+0.084	<.001	<.001	3	13
SCLC	Positive regulation of CD4-positive, alpha-beta T cell activation →	+0.076	+0.096	.001	.003	2	14
STAD	Regulation of lymphocyte chemotaxis →	+0.071	+0.134	<.001	<.001	3	13
STAD	Positive regulation of lipid kinase activity →	+0.055	+0.106	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,680 associations by consensus.

Positive regulation of the force of heart contraction by MYL2 expression — PAAD

Explore this box plot interactively →