MYL12A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYL12A protein abundance is significantly associated with the RNA expression of many other genes, with 3,174 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MYL12A-associated genes across cancer lineages are THY1, COL16A1, and TMEM35A. Each is linked with MYL12A in more than 2 cancer types. Because this analysis shows association rather than direction, both MYL12A-to-partner and partner-to-MYL12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYL12A versus THY1 in BRCA, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL12A→partner) and Y-score (partner→MYL12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATHY1 →+1.295+0.892<.001<.00133
CCRCCCOL16A1 →+1.416+0.480<.001<.00133
UCECTMEM35A →+0.774+0.934.005.00632
BRCAEIF4E →-0.545-0.746.005<.00132
UCECCEL →+1.293+0.849<.001.00332
UCECNR2E3 →+1.895+0.837<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,174 associations by consensus.

MYL12A vs THY1 — BRCA

Per-sample scatter of MYL12A vs THY1 in BRCA (Pearson r = 0.49).

Explore this scatter interactively →

Exploration