MYL12A

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MYL12A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,699 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MYL12A-associated GO terms across cancer lineages are Iron coordination entity transport, Cellular response to environmental stimulus, and Negative regulation of extrinsic apoptotic signaling pathway. Each is linked with MYL12A in more than 10 cancer types. Because this analysis shows association rather than direction, both MYL12A-to-partner and partner-to-MYL12A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Iron coordination entity transport grouped by MYL12A-low versus MYL12A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL12A→partner) and Y-score (partner→MYL12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCIron coordination entity transport →-0.175-1.415<.001.002311
LUNG_SCLCCellular response to environmental stimulus →+0.049+1.208<.001.006310
BONENegative regulation of extrinsic apoptotic signaling pathway →+0.136+0.963<.001<.001310
BONEWound healing →+0.133+1.211<.001<.001310
LUNG_SCLCCellular response to abiotic stimulus →+0.049+1.208<.001.006310
BONEMembrane assembly →+0.098+1.219<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,699 associations by consensus.

Iron coordination entity transport by MYL12A expression — LUNG_NSCLC_LUSC

Box plot of Iron coordination entity transport in MYL12A-low vs MYL12A-high samples in LUNG_NSCLC_LUSC.

Explore this box plot interactively →

Exploration