MYL10

Across TCGA patient cohorts, MYL10 mutation is significantly associated with the RNA expression of many other genes, with 637 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYL10-associated genes across cancer lineages are MTCO1P44, SNORD116-11, and RNA5SP155. Each is linked with MYL10 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYL10-to-partner and partner-to-MYL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCO1P44 grouped by MYL10-low versus MYL10-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL10→partner) and Y-score (partner→MYL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MTCO1P44 →	+0.114	+7.954	<.001	.008	3	2
SKCM	SNORD116-11 →	+0.248	+4.897	<.001	.002	3	2
UCEC	RNA5SP155 →	+0.420	+2.314	.007	.002	3	2
SKCM	RPL35AP15 →	+0.332	+3.160	<.001	.006	3	2
HNSC	UBTFL3 →	+0.079	+7.954	<.001	.008	3	1
HNSC	RNU4-88P →	+0.653	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 637 associations by consensus.

MTCO1P44 by MYL10 expression — HNSC

Explore this box plot interactively →