MYHAS

Across TCGA pan-cancer cohorts, MYHAS RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of MYHAS’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where MYHAS RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MYHAS is over-expressed in tumor, although a few such as KICH and HNSC show the opposite, repressed pattern.

LUAD, LUSC, and KICH are the cancer types where MYHAS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYHAS RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+0.105	<.001	6	view →
LUSC	Male	All	+0.278	<.001	5	view →
KICH	Female	II,III,IV	−0.218	<.001	5	view →
LIHC	All	All	+0.099	.001	5	view →
CHOL	Female	All	+0.106	<.001	3	view →
BLCA	Female	All	+0.090	.010	3	view →
HNSC	Male	All	−0.936	.010	2	view →
PAAD	All	All	+0.355	.034	2	view →
PRAD	All	All	−0.143	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

MYHAS–LUAD

Open the LUAD breakdown →