MYH7

Across TCGA cell cohorts, MYH7 RNA expression is significantly associated with the go_rna of many other GO terms, with 530 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MYH7-associated GO terms across cancer lineages are Positive regulation of myoblast fusion, Nuclear receptor-mediated glucocorticoid signaling pathway, and Striated muscle cell development. Each is linked with MYH7 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYH7-to-partner and partner-to-MYH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of myoblast fusion grouped by MYH7-low versus MYH7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH7→partner) and Y-score (partner→MYH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of myoblast fusion →	-0.200	-0.024	.002	.003	3	3
BONE	Nuclear receptor-mediated glucocorticoid signaling pathway →	-0.106	-0.041	<.001	.001	3	3
BONE	Striated muscle cell development →	-0.083	-0.037	.004	.008	3	3
CNS	Internal protein amino acid acetylation →	+0.083	+0.078	<.001	.006	3	3
CNS	Regulation of the force of skeletal muscle contraction →	+0.120	+0.153	<.001	.004	3	3
CNS	Regulation of skeletal muscle contraction by chemo-mechanical energy conversion →	+0.120	+0.153	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 530 associations by consensus.

Positive regulation of myoblast fusion by MYH7 expression — BONE

Explore this box plot interactively →