Across TCGA patient cohorts, MYH6 protein abundance is significantly associated with the RNA expression of many other genes, with 782 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MYH6-associated genes across cancer lineages are KLK8, DHX30, and LRRIQ1. Each is linked with MYH6 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYH6-to-partner and partner-to-MYH6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH6→partner) and Y-score (partner→MYH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KLK8 →	-2.046	-0.817	.002	.002	3	1
LUAD	DHX30 →	+0.396	+0.656	.002	.003	3	1
LUAD	LRRIQ1 →	-1.248	-0.656	.004	.003	3	1
LUAD	ARPC5L →	+0.675	+0.656	<.001	.003	3	1
LUAD	CYP1A1 →	-0.207	-0.813	.007	.005	3	1
LUAD	UBA3 →	+0.398	+0.656	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 782 associations by consensus.

Exploration

MYH6 survival (RNA) · tumor vs normal (RNA) · all MYH6 data types