MYH4

Across TCGA cell cohorts, MYH4 RNA expression is significantly associated with the go_rna of many other GO terms, with 279 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYH4-associated GO terms across cancer lineages are Positive regulation of mitochondrial fusion, Glycoprotein catabolic process, and Ear morphogenesis. Each is linked with MYH4 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYH4-to-partner and partner-to-MYH4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial fusion grouped by MYH4-low versus MYH4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH4→partner) and Y-score (partner→MYH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of mitochondrial fusion →	+0.124	+0.019	.001	.002	3	2
SOFT_TISSUE	Glycoprotein catabolic process →	-0.081	-0.019	.001	.003	3	2
STOMACH	Ear morphogenesis →	+0.081	+0.255	<.001	.009	3	2
STOMACH	Inner ear morphogenesis →	+0.095	+0.183	<.001	.008	2	3
STOMACH	Hemoglobin biosynthetic process →	+0.208	+0.182	.001	.009	3	2
STOMACH	Negative regulation of D-glucose import across plasma membrane →	+0.134	+0.183	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 279 associations by consensus.

Positive regulation of mitochondrial fusion by MYH4 expression — SOFT_TISSUE

Explore this box plot interactively →