MYH3

Across TCGA patient cohorts, MYH3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,996 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MYH3-associated proteins across cancer lineages are HDGFL3, VAMP8, and PSIP1. Each is linked with MYH3 in more than 5 cancer types. Because this analysis shows association rather than direction, both MYH3-to-partner and partner-to-MYH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYH3 versus HDGFL3 in BRCA, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH3→partner) and Y-score (partner→MYH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL3 →	+0.564	+0.354	.002	.004	3	5
GBM	VAMP8 →	-0.595	-0.452	.002	<.001	3	5
GBM	PSIP1 →	+0.404	+0.295	<.001	<.001	3	5
BRCA	SARM1 →	+0.412	+0.480	.002	<.001	3	5
BRCA	FERMT2 →	+0.479	+0.340	<.001	.003	2	6
CCRCC	KANK2 →	+0.500	+0.514	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,996 associations by consensus.

MYH3 vs HDGFL3 — BRCA

Explore this scatter interactively →