MYH3

Across TCGA cell cohorts, MYH3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,657 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYH3-associated GO terms across cancer lineages are Spliceosomal complex assembly, Establishment of RNA localization, and Nucleic acid catabolic process. Each is linked with MYH3 in more than 13 cancer types. Because this analysis shows association rather than direction, both MYH3-to-partner and partner-to-MYH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal complex assembly grouped by MYH3-low versus MYH3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH3→partner) and Y-score (partner→MYH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Spliceosomal complex assembly →	+0.113	+0.950	<.001	<.001	3	14
BONE	Establishment of RNA localization →	+0.108	+0.850	<.001	<.001	3	14
LIVER	Nucleic acid catabolic process →	+0.060	+1.244	.006	.001	3	12
OESOPHAGUS	RNA localization →	+0.095	+0.922	.001	.004	2	13
BONE	Regulation of telomere maintenance →	+0.100	+1.523	<.001	.001	3	12
LUNG_SCLC	Regulation of telomere maintenance via telomerase →	+0.082	+1.325	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,657 associations by consensus.

Spliceosomal complex assembly by MYH3 expression — BONE

Explore this box plot interactively →