MYH16

Across TCGA patient cohorts, MYH16 mutation is significantly associated with the RNA expression of many other genes, with 2,224 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYH16-associated genes across cancer lineages are RNA5SP422, AQP7P3, and LINC01943. Each is linked with MYH16 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYH16-to-partner and partner-to-MYH16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by MYH16-low versus MYH16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH16→partner) and Y-score (partner→MYH16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP422 →	+0.608	+2.086	.006	.009	3	2
UCEC	AQP7P3 →	+0.037	+3.582	<.001	.002	3	1
UCEC	LINC01943 →	+0.625	+3.353	<.001	.005	3	1
UCEC	ARRDC3-AS1 →	+0.345	+3.491	<.001	.002	3	1
UCEC	IGHV3OR16-6 →	+0.425	+2.932	.009	<.001	3	1
UCEC	IGKV1OR2-118 →	+0.201	+2.688	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,224 associations by consensus.

RNA5SP422 by MYH16 expression — UCEC

Explore this box plot interactively →