MYH14

Across TCGA cell cohorts, MYH14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,400 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MYH14-associated GO terms across cancer lineages are Regulation of nuclear-transcribed mRNA poly(A) tail shortening, Cellular response to alcohol, and Establishment of epithelial cell apical/basal polarity. Each is linked with MYH14 in more than 11 cancer types. Because this analysis shows association rather than direction, both MYH14-to-partner and partner-to-MYH14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear-transcribed mRNA poly(A) tail shortening grouped by MYH14-low versus MYH14-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH14→partner) and Y-score (partner→MYH14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.087	+1.951	.001	.003	3	12
URINARY_TRACT	Cellular response to alcohol →	+0.126	+3.236	.002	.002	3	11
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	-0.220	-3.572	.001	<.001	3	11
BONE	Bundle of His cell-Purkinje myocyte adhesion involved in cell communication →	+0.988	+0.865	.005	.006	3	11
URINARY_TRACT	T cell mediated cytotoxicity →	+0.201	+3.927	<.001	<.001	3	10
LIVER	Megakaryocyte differentiation →	-0.142	-3.310	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,400 associations by consensus.

Regulation of nuclear-transcribed mRNA poly(A) tail shortening by MYH14 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →