MYH11

Across TCGA cell cohorts, MYH11 RNA expression is significantly associated with the RNA expression of many other genes, with 8,402 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYH11-associated genes across cancer lineages are SH2B1, FLYWCH1, and TAOK2. Each is linked with MYH11 in more than 8 cancer types. Because this analysis shows association rather than direction, both MYH11-to-partner and partner-to-MYH11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYH11 versus SH2B1 in BLOOD_Leukemia, with a Pearson correlation of 0.37.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH11→partner) and Y-score (partner→MYH11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SH2B1 →	+1.264	+0.605	<.001	<.001	2	9
URINARY_TRACT	FLYWCH1 →	+1.147	+0.269	<.001	<.001	3	8
SOFT_TISSUE	TAOK2 →	+1.111	+0.786	<.001	.003	3	7
BLOOD_Lymphoma	ZNF764 →	+1.097	+1.021	<.001	.003	2	8
BLOOD_Lymphoma	NFATC2IP →	+1.281	+1.056	<.001	<.001	2	8
BLOOD_Lymphoma	MNT →	+1.488	+0.605	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,402 associations by consensus.

MYH11 vs SH2B1 — BLOOD_Leukemia

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