MYH10

Across TCGA cell cohorts, MYH10 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,568 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYH10-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Protein-DNA complex assembly, and Regulation of chromosome organization. Each is linked with MYH10 in more than 17 cancer types. Because this analysis shows association rather than direction, both MYH10-to-partner and partner-to-MYH10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by MYH10-low versus MYH10-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH10→partner) and Y-score (partner→MYH10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.064	+1.634	<.001	<.001	3	18
OESOPHAGUS	Protein-DNA complex assembly →	+0.069	+2.460	.001	.004	3	18
SOFT_TISSUE	Regulation of chromosome organization →	+0.089	+1.683	<.001	.001	3	17
BLOOD_Lymphoma	DNA-templated transcription initiation →	+0.067	+2.449	<.001	<.001	3	17
OESOPHAGUS	Protein-DNA complex organization →	+0.078	+2.758	<.001	.002	3	17
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.108	+1.933	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,568 associations by consensus.

Epigenetic regulation of gene expression by MYH10 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →