Across TCGA pan-cancer cohorts, MYG1P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MYG1P1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where MYG1P1 RNA is repressed in tumor relative to normal tissue. In most cancer types MYG1P1 is over-expressed in tumor, although a few such as KICH and PAAD show the opposite, repressed pattern.
KICH, PAAD, and COAD are the cancer types where MYG1P1 tumor–normal differential expression is most reproducible.