MYG1

Across TCGA patient cohorts, MYG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,168 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MYG1-associated GO terms across cancer lineages are [4Fe-4S] cluster assembly, Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, and COPII-coated vesicle cargo loading. Each is linked with MYG1 in more than 24 cancer types. Because this analysis shows association rather than direction, both MYG1-to-partner and partner-to-MYG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [4Fe-4S] cluster assembly grouped by MYG1-low versus MYG1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYG1→partner) and Y-score (partner→MYG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	[4Fe-4S] cluster assembly →	+0.074	+0.460	<.001	<.001	3	25
SCLC	Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway →	-0.084	-0.427	.003	.002	2	25
DLBC	COPII-coated vesicle cargo loading →	-0.090	-0.418	<.001	<.001	3	23
DLBC	Interleukin-5-mediated signaling pathway →	-0.087	-0.407	<.001	<.001	3	23
SCLC	tRNA thio-modification →	+0.091	+0.439	.002	<.001	2	24
THYM	Positive regulation of MHC class I biosynthetic process →	-0.075	-0.279	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,168 associations by consensus.

[4Fe-4S] cluster assembly by MYG1 expression — DLBC

Explore this box plot interactively →