MYG1

Across TCGA cell cohorts, MYG1 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYG1-associated genes across cancer lineages are RGSL1, COX6A2, and OR1L6. Each is linked with MYG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYG1-to-partner and partner-to-MYG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RGSL1 grouped by MYG1-low versus MYG1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYG1→partner) and Y-score (partner→MYG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RGSL1 →	+0.015	+4.977	.002	.007	3	1
LARGE_INTESTINE	COX6A2 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR1L6 →	+0.018	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR10H5 →	+0.018	+3.347	<.001	.005	3	1
LARGE_INTESTINE	PTCHD3 →	+0.019	+3.632	<.001	.003	3	1
LARGE_INTESTINE	PRR23B →	+0.004	+3.632	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

RGSL1 by MYG1 expression — SKIN

Explore this box plot interactively →