MYF5

Across TCGA patient cohorts, MYF5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,804 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MYF5-associated GO terms across cancer lineages are Cardiac muscle contraction, Positive regulation of cation channel activity, and Muscle cell development. Each is linked with MYF5 in more than 6 cancer types. Because this analysis shows association rather than direction, both MYF5-to-partner and partner-to-MYF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiac muscle contraction grouped by MYF5-low versus MYF5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYF5→partner) and Y-score (partner→MYF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cardiac muscle contraction →	+0.049	+0.036	<.001	.004	3	7
UCS	Positive regulation of cation channel activity →	+0.046	+3.823	<.001	<.001	3	6
UCS	Muscle cell development →	+0.058	+2.438	<.001	<.001	3	6
STAD	Connective tissue development →	+0.072	+0.021	<.001	.005	3	6
STAD	Obsolete positive regulation of ER-associated ubiquitin-dependent protein catabolic process →	+0.100	+0.021	<.001	.005	3	6
TGCT	Regulation of animal organ morphogenesis →	+0.064	+0.556	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,804 associations by consensus.

Cardiac muscle contraction by MYF5 expression — STAD

Explore this box plot interactively →