MYF5

Across TCGA patient cohorts, MYF5 protein abundance is significantly associated with the RNA expression of many other genes, with 132 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MYF5-associated genes across cancer lineages are NPM3, TMEM14C, and SDC4. Each is linked with MYF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYF5-to-partner and partner-to-MYF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYF5 versus NPM3 in CCRCC, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYF5→partner) and Y-score (partner→MYF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NPM3 →	-1.246	-1.156	<.001	.001	3	1
CCRCC	TMEM14C →	-0.625	-1.174	<.001	.003	3	1
CCRCC	SDC4 →	+1.342	+1.175	.003	.003	3	1
CCRCC	SNRPA1 →	-0.702	-1.139	.002	.006	3	1
CCRCC	TMEM14B →	-0.742	-1.174	.003	.003	3	1
CCRCC	FBXO32 →	+1.142	+1.117	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 132 associations by consensus.

MYF5 vs NPM3 — CCRCC

Explore this scatter interactively →