MYF5

Across TCGA cell cohorts, MYF5 RNA expression is significantly associated with the mutation status of many other genes, with 187 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MYF5-associated genes across cancer lineages are TSC1, DLGAP4, and TCHH. Each is linked with MYF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYF5-to-partner and partner-to-MYF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSC1 grouped by MYF5-low versus MYF5-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYF5→partner) and Y-score (partner→MYF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TSC1 →	+5.000	+0.016	.006	<.001	3	2
LUNG_NSCLC_LUAD	DLGAP4 →	+4.266	+0.663	.004	<.001	3	2
BLOOD_Leukemia	TCHH →	+2.501	+0.003	.003	<.001	3	2
BREAST	ITGA3 →	+5.169	+0.023	.005	<.001	3	2
CNS	WDFY3 →	+3.321	+0.253	.003	.002	3	2
CNS	ZNF407 →	+4.321	+0.567	.009	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 187 associations by consensus.

TSC1 by MYF5 expression — PANCREAS

Explore this box plot interactively →