MYF5

Across TCGA cell cohorts, MYF5 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MYF5-associated genes across cancer lineages are HTR1A, ELOA3DP, and OR6Q1. Each is linked with MYF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYF5-to-partner and partner-to-MYF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR1A grouped by MYF5-low versus MYF5-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYF5→partner) and Y-score (partner→MYF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	HTR1A →	+0.006	+5.415	<.001	.004	3	1
LARGE_INTESTINE	ELOA3DP →	+0.023	+4.273	.003	.006	3	1
LARGE_INTESTINE	OR6Q1 →	+0.022	+5.022	<.001	.002	3	1
BLOOD_Lymphoma	LCE2A →	+0.041	+5.209	<.001	.005	3	1
LUNG_NSCLC_LUAD	FEZF2 →	+0.013	+4.189	<.001	.002	3	1
LUNG_NSCLC_LUAD	SLC6A18 →	+0.027	+3.947	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

HTR1A by MYF5 expression — SKIN

Explore this box plot interactively →