MYEF2

Across TCGA patient cohorts, MYEF2 protein abundance is significantly associated with the RNA expression of many other genes, with 20,713 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MYEF2-associated genes across cancer lineages are CXXC4, PATZ1, and DTWD1. Each is linked with MYEF2 in more than 7 cancer types. Because this analysis shows association rather than direction, both MYEF2-to-partner and partner-to-MYEF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYEF2 versus CXXC4 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYEF2→partner) and Y-score (partner→MYEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CXXC4 →	+1.186	+0.418	<.001	<.001	3	8
BRCA	PATZ1 →	+0.846	+0.803	<.001	<.001	3	7
HNSC	DTWD1 →	+0.446	+0.898	<.001	<.001	3	7
HNSC	GSDMC →	-1.251	-0.754	<.001	<.001	3	7
BRCA	WDR17 →	+1.003	+0.742	<.001	<.001	3	7
BRCA	KLHDC9 →	+1.813	+0.716	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,713 associations by consensus.

MYEF2 vs CXXC4 — GBM

Explore this scatter interactively →