MYEF2

Across TCGA cell cohorts, MYEF2 mutation is significantly associated with the drug of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYEF2-associated genes across cancer lineages are Gemcitabine, Luminespib, and Entospletinib. Each is linked with MYEF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYEF2-to-partner and partner-to-MYEF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gemcitabine grouped by MYEF2-low versus MYEF2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYEF2→partner) and Y-score (partner→MYEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Gemcitabine →	+0.817	+2.807	.033	.046	3	1
LARGE_INTESTINE	Luminespib →	+0.611	+2.868	.034	.022	3	1
LARGE_INTESTINE	Entospletinib →	+0.411	+2.868	.023	.022	3	1
LARGE_INTESTINE	CDK9_5038 →	+0.591	+3.129	.023	.014	3	1
LARGE_INTESTINE	Teniposide →	+0.510	+2.710	.044	.027	3	1
LARGE_INTESTINE	Fludarabine →	+0.533	+2.871	.034	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Gemcitabine by MYEF2 expression — LARGE_INTESTINE

Explore this box plot interactively →