MYDGF

Across TCGA patient cohorts, MYDGF mutation is significantly associated with the RNA expression of many other genes, with 190 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYDGF-associated genes across cancer lineages are RNU6-728P, LINC00363, and RNA5SP234. Each is linked with MYDGF in more than 1 cancer types. Because this analysis shows association rather than direction, both MYDGF-to-partner and partner-to-MYDGF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-728P grouped by MYDGF-low versus MYDGF-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYDGF→partner) and Y-score (partner→MYDGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-728P →	+0.267	+7.731	<.001	.009	3	2
UCEC	LINC00363 →	+0.182	+3.612	<.001	.003	3	2
BRCA	RNA5SP234 →	+0.237	+8.055	<.001	.007	3	1
BRCA	LINC01628 →	+0.103	+8.055	<.001	.007	3	1
BRCA	USP9YP2 →	+0.044	+7.731	<.001	.009	3	1
UCEC	LINC00706 →	+0.107	+2.431	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 190 associations by consensus.

RNU6-728P by MYDGF expression — BRCA

Explore this box plot interactively →